Useful properties of vitamin B13
All vitamins are important, but among them there are not enough known. For example, B13 does not belong to the essential and vital substances, but still it helps to maintain health.
What is this vitamin?
Vitamin B13, also called orotic acid or orotam, is not a full-fledged vitamin, but a vitamin-like substance that is synthesized by the human body and is present in certain foods. It dissolves poorly in the aquatic environment and is destroyed at elevated temperatures or in the light.
For the first time orot acid was found at the beginning of the last century in waste products of wine. A year later she was found in cow's milk, and then in the female breast. In the 30s, scientists learned the structure of the substance, and later discovered the growth factor of rats and chickens, which they called vitamin B13. In the 50's it was confirmed that this vitamin and orotate are absolutely identical substances. Even later, it became clear that orotovoya acid is excreted in the intestine, so a full-fledged vitamin should not be called and does not have all the necessary properties.
What are the functions of this vitamin?
What is orotic acid for? Vitamin B13 performs the following functions:
- Such a substance takes an active part in many metabolic processes and reactions occurring in the human body. So, it ensures the proper use of glucose, the production of ribose, the preservation of adenosine triphosphate stores, the formation of phospholipids, the synthesis of nucleic acids and proteins. Thanks to orotate it becomes possible to form other equally important vitamins, such as B12, pantothenic acid, folic acid.
- Orotic acid ensures the proper development of tissues, the formation of new healthy cells, without it, harmonious growth is impossible at the stage of intrauterine development and in childhood.
- Vitamin normalizes the contractile activity of muscles, provides a full-fledged supply of muscle tissue and forms in them the energy reserve necessary for development and smooth functioning.
- Orotate is useful for the body, as it significantly improves the liver: it stimulates the restoration of its cells, normalizes functioning and minimizes the risks of obesity of this organ.
- The substance is necessary for the heart, as it strengthens the myocardium and normalizes the heart rate.
- Orotic acid helps to reduce the level of "bad" cholesterol and thereby ensure the prevention of atherosclerosis.
- B13 is useful for women, as it normalizes reproductive functions and contributes to the harmonious formation of the fetus.
- Orotate accelerates the regeneration of tissues, slows down their aging processes.
- The substance is used by the body to form epithelial tissues and helps restore the structure of the skin.
Orotic acid is synthesized in optimal volumes by the intestines, but, according to many scientists, the need is on average 1-2 grams. For infants, the norm is about 0.2-0.4 g, for adolescents - about 1-1.5, for adults - about 1.5-2 grams. During pregnancy, the need increases to 2.7-3 g, as in the period of breastfeeding.
Consumption can increase with intense stress, significant blood loss, after the surgery, as well as in some pathologies and diseases (they will be considered below).
How to get?
B13 is present in natural products, for example dairy products, in which orotic acid is the most. And the most significant content is found in horse milk, although the substance is present in the female breast, due to which it enters the body of the newborn. Also B13 can be obtained from root vegetables, pork or beef liver, yeast.
Orotic acid is present in some biological active additives and vitamin preparations, but in its pure form it is absorbed extremely poorly, therefore it is used in pharmacology as a compound - potassium orotate.
When should I take orotic acid?
The use of drugs with potassium orotate is recommended in the following cases:
- certain liver diseases, for example, hepatitis, cirrhosis, obesity;
- dermatological diseases: neurodermatitis, ichthyosis, eczema, dermatitis, psoriasis and some others;
- increased cholesterol, atherosclerosis;
- ulcerative lesions of internal organs, for example, duodenum, stomach;
- heart failure;
- heart attacks, myocarditis;
- muscular hypotrophy;
- delayed development or growth in children;
- problems with conception;
- pregnancy planning;
- rehabilitation after severe diseases or operations;
- increased physical activity.
Orotate may interact with certain other substances. For example, it minimizes the toxic properties of cardiac glycosides, improves the assimilation of B vitamins, and ensures the tolerability of certain medications (steroids and certain antibiotics).
Tip: Orotic acid is used not only for preventive and therapeutic purposes, but also in cosmetology. So, it can be a part of various creams and masks.
Lack of vitamin B13
Since orotic acid is synthesized by the human body, its deficiency is extremely rare. In addition, the substance is not a full-fledged vitamin, so even with a prolonged shortage of serious consequences do not occur. But in certain cases, acute and pathological deficits can lead to symptoms such as muscle weakness, stunted growth, changes in body weight, and certain metabolic disorders.
Excess vitamin B13 derived from food is almost impossible.But overdose is likely when taking drugs on the basis of potassium orotate. It can be expressed in the form of skin rashes, liver dystrophy, nausea or vomiting, digestive disorders, flatulence.
Although vitamin B13 is not as necessary as everyone else, it performs several important functions. This substance is produced by the body, but sometimes it needs additional intake.
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